Apremilast is used in the treatment of Plaque psoriasis. It is used in patients who have had an inadequate response or have been intolerant to a previous medication.

Apremilast (Otezla) is used to treat plaque psoriasis, psoriatic arthritis, and Behçet's disease in specific patients. Apremilast tablets help improve plaque psoriasis for clearer skin and reduce inflammation and symptoms such as pain, redness, and swelling in psoriatic arthritis and Behcet's disease.